Colorectal Conundrum for January 8:
A newborn is diagnosed with HD by suction rectal biopsy and this is the contrast study. The biopsy shows no ganglion cells and hypertrophic nerves, but the pathologist notes significant inflammation. Irrigations are going well, and the abdomen is soft and flat. What would you do? Proceed with pull-through or send home on irrigations and delay the pull-through for several months. Which is your usual routine? Does the pathology findings influence that decision?
Answer:
This is a relatively common conundrum for the surgeon, taking care of patient with diagnosed HD, doing well on irrigations, but recovering from HAEC, or on biopsy showing evidence of inflammation. In such a case I would be inclined to do longer term irrigations, send the baby home (provided irrigations are going well), and do the pull-through for what looks like typical sigmoid disease at 2 to 3 months of life.